Design & Surface Properties of Materials in Biomedical Engineering

(Department)  Biomedical Engineering         (Division)      Biomaterials and Tissue Engineering
 
 (Level and Major) 
 

Course Title                Design & Surface Properties of Materials in Biomedical Engineering
 
Number of Credits       3             Prerequisite
 

Aims and objectives: The success of materials in medicine is greatly influenced by the interactions that take place between material surfaces and biological systems. Since, material surface properties play the key role in the occurrence of particular phenomena in bio/non-bio interfaces; knowledge of design, process and characterization of biomaterial surface are of great importance in biomedical engineering. This course discusses biomedical surface roles and addresses surface related issues in
.
  1. Surface properties of materials
  • Surface energy and related phenomena
  • Wettability models -contact angle
  • Surface tension, contact angle measurement techniques
  • Surface adsorption and related models
  • Surface topography
 
  1. Biomaterials surface interactions with the biological environment
  • Bioinert and bioactive surfaces
  • Proteins for surface structuring
  • Surface-Grafted polymer brushes
  • Inhibiting nonspecific protein adsorption: Mechanisms, Methods, and Materials
  • Surface properties and design for controlling stem cell behavior
 
  1. Surface Modifications
  • Micro- and nano-patterning of biomaterial surfaces
  • Plasma-Assisted surface treatments and modifications for biomedical applications
  • Biological and bioinspired micro- and nanostructured adhesives
  • Stimuli-responsive surfaces for biomedical applications
  • Interfacial self-assembly
  • Surface modification by electrochemical method for biomedical applications
  • Surface modification by laser for biomedical applications
 
  1. Surface Analysis
Microscopy and spectroscopy techniques for surface analysis

References:
Biomaterials Surface Science, Edited by Andreas Taubert, Joao F. Mano, and J. Carlos Rodriguez-Cabello

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