Mahdi Shafieian
Assistant Professor
Department of Biomedical Engineering
Biomaterial
Department of Biomedical Engineering
Biomaterial
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h-index (Scopus):
13.00
Citations (Scopus):
723
Supervised PhD Theses
#
Thesis title
By
Date
1
Investigation of the effect of test design on the mechanical properties of brain tissue under traumatic conditions using mechanical experiments
HADI NOSRATI
2026 Jun
2
Production and optimization of wound dressing consisting of electrospinned nanofibers from sulfated alginate loaded with antibiotic drugs
MARYAM ZARE GACHI & ATEFEH SOLOUK MOFRAD
Other Supervisor:
Other Supervisor:
2025 Jun
Supervised MSc Theses
#
Thesis title
By
Date
1
Fabrication and characterization of mechanical properties of a 3D scaffold consisting of hyaluronic acid and extracellular matrix derived from fibroblast cell for central nerve tissue regeneration
ALIREZA GHOFRANI
2024 Feb
2
Study of the changes in the mechanical properties of the brain tissue due to preconditioning
AVA MAZHARI
2023 Oct
3
Determining the mechanical properties of the lateral temporomandibular ligament
MAEDE RAHIMI & SEYYED ATAOLLAH HASHEMI
Other Supervisor:
Other Supervisor:
2023 Sep
4
Simulation, optimization and fabrication of bone scaffolds with ceramic-polymer composites using 3D printer
MOJTABA EFFATPANAH HESARI
Other Supervisor: SAEED SABER SAMANDARI
Other Supervisor: SAEED SABER SAMANDARI
2023 Jun
5
Predicting Abdominal Aortic Aneurysm Growth Using Machine Learning methods and Clinical Data
FAEZE JAHANI & MALIKEH NABAEI
Other Supervisor:
Other Supervisor:
2023 Jun
6
The Role of Microstructural Components in the Mechanical Behavior of Injured Brain
Tissue: A Finite Element Study
ANIS ALLAHDINIAN
2023 Apr
7
Fabriction and characterization of a multilayer scaffold based on silk fibroin and acellular amniotic membrane seeded with adipose-derived mesenchymal stem cells for bladder regeneration
MELINA MAMDOOHI
2022 Jun
8
Evaluation of the effect of functional rehabilitation on the pathophysiology of central nervous tissue
NEGAR NEKAHI
2022 Mar
9
A mathematical model to study biophysical parameters in microneedle process
ZAHRA AZIMI
Other Supervisor: NABIOLAH ABOLFATHI
Other Supervisor: NABIOLAH ABOLFATHI
2022 Mar
10
A comparative study of the damage exerted by impact loading in the mandible-dental implant and mandible-tooth constructs
AMIR ABBAS MOSLEHI & GHOLAMREZA ROUHI
Other Supervisor:
Other Supervisor:
2021 Oct
11
Investingating the effect of pore size and shape in improvement of mechanical properties of bone scaffold that made of PLA and PCL filament and printing the optimized model with FDM 3d printer
BEHZAD PARPANCHI
Other Supervisor: SAEED SABER SAMANDARI
Other Supervisor: SAEED SABER SAMANDARI
2021 Aug
12
?Evaluation of the electrical stimulation on extent of fibroblast cell-derived ECM deposition on the conductive nanofibrous scaffolds
QAZAL MOHAMMADI
2021 Jan
13
Modification of alginate hydrogel with fibroblast- and Schwann cells- derived ECM to guide the differentiation of mesenchymal stem cells (MSCs) toward neuron-like cells
ZAHRA AYAR DULABI
2020 Feb
14
Optimization of Polymer-Ceramic Composite Scaffold Function for Repairing Comminuted Bone Defect
MAHSHID ZAFAR JAFARZADEH NOGHANI & MEHRAN SOLATI
Other Supervisor:
Other Supervisor:
2020 Jan
15
Analysis of central nervous cells to mechanical loading using finite element modeling
FATEMEH ATASHGAR
2019 Oct
16
fabrication and characterization of composite scaffold for reconstruction of comminutted fracture of long bones
HAMIDREZA BARZANOUNI
2019 Feb
17
Reducing the risk of head injury in a motorcycle with modification the
mechanical properties of foam used in motorcycle helmet
ANAHITA KHOOBAN
2019 Feb
18
Fabrication of 3D composite based on PCL/bioactive nanoparticles by 3D printing method
ZAHRA ABDIZADEH KALKHORAN
2019 Feb
19
synthesis and Evaluation of Antibacterial Activity of cardiac patch based on reduced graphene oxide
MOHADESEH POURMOKHTARI
2018 Oct
20
Mechanical Properties Reinforcement of synthetic vessels based on polyurethane by carbon nanotube (CNTs
ZAHRA EIVAZI ZADEH & ATEFEH SOLOUK MOFRAD
Other Supervisor:
Other Supervisor:
2018 Oct
21
Modeling of concentric contraction in order to compression optimization of the effect of acentric exercises by concentric exercising method
MOHAMMADREZA ZARE EMAMI
2018 Sep
22
Characterization of nonlinear mechanical properties of single cell by micropipette aspiration
SAEED MOHAMMADPOUR
2018 Jul
23
Biomechanical analysis of the probability of injury to occupants in frontal impact
TAYEBE ABASI
2018 Feb
24
Determining the optimum parameters of soccer headgear for female players
SHIMA ZEINALI
2017 Feb
25
Analysis of whiplash injuries in low speed rear end accidents
PARYA AVAZNEJAD & NABIOLAH ABOLFATHI
Other Supervisor:
Other Supervisor:
2017 Feb
26
Anisotropic properties of brain tissue using DTI method
FARGOL REZAYARAGHI
2017 Feb
27
Characterization and comparison of the viscoelastic behavior of natural and synthetic blood vessels
FOROUGH ASKARI SIAHOOEI & ATEFEH SOLOUK MOFRAD
Other Supervisor:
Other Supervisor:
2015 Feb
28
Developing a mechanical model for the behavior of an engineered tendon using a naturally derivedECM scaffold
RAZIEH MAHOOTCHI
Other Supervisor: MOHAMMAD TAFAZZOLI-SHADPOUR
Other Supervisor: MOHAMMAD TAFAZZOLI-SHADPOUR
2025 Aug
Journal Papers
1
M. Shafieian, N. Abolfathi, Y. Youseph, "Caredesign: A Needs-Finding Framework for Enhancing Healthcare Service Innovation in Low-and Middle-Income Countries", Annals of Biomedical Engineering, 2026 Feb
vol. 54,
no. 2,
pp.613-620,
2026.
2
H. Barzanouni, B.H. Arezou, M. Solati, B. Amir, M. Shafieian, "3DPrinted PLA: TCP Scaffolds: Fabrication and Evaluation for Bone Regeneration in LoadBearing Defects", Polymers For Advanced Technologies, 2025 Dec
vol. 36,
no. 12,
pp.70466-70479,
2025.
3
M. Mamdoohi, M. Shafieian, Z. Hassannejad, "A TripleLayered Composite Scaffold of Silk Fibroin and Decellularized Amniotic Membrane for Bladder Tissue Engineering", Macromolecular Bioscience, 2025 Nov
vol. 25,
no. 11,
pp.157-177,
2025.
4
H. Nosrati, M. Shafieian, N. Abolfathi, "The importance of brain thermomechanics in clinical neurosurgery and simulations", Journal of Thermal Biology, 2025 Oct
vol. 1,
no. 1,
pp.104292-104302,
2025.
5
H. Nosrati, M. Shafieian, N. Abolfathi, "A Comprehensive Analysis of Inconsistencies in the Brain's Conventional Ex Vivo Mechanical Experiments", Annals of Biomedical Engineering, 2025 Aug
vol. 53,
no. 8,
pp.1777-1796,
2025.
6
A. Fatemeh, M. Shafieian, N. Abolfathi, "From structure to mechanics: exploring the role of axons and interconnections in anisotropic behavior of brain white matter", Biomechanics and Modeling In Mechanobiology, 2025 Jun
vol. 24,
no. 3,
pp.779-810,
2025.
7
M. Zare Gachi, A. Solouk Mofrad, M. Shafieian, Hamed Daemi, "Chemical structure of antibiotics determines their release rate from drug-loaded poly(vinyl alcohol)/sodium sulfated alginate nanofibrous wound dressings", International Journal of Biological Macromolecules, 2025 May
vol. 307,
no. 1,
pp.1-11,
2025.
8
Z. Eivazi Zadeh, F. Eskandari, M. Shafieian, A. Solouk Mofrad, M. Haghbin Nazarpak, "The importance of polyurethane/carbon nanotubes composites fabrication method to mimic mechanical behavior of different types of soft tissues", Polymer Bulletin, 2023 Jan
vol. 80,
no. 1,
pp.1-12,
2023.
9
A. Fatemeh, M. Shafieian, N. Abolfathi, "The effect of the properties of cell nucleus and underlying substrate on the response of finite element models of astrocytes undergoing mechanical stimulations", Computer Methods In Biomechanics and Biomedical Engineering, 2022 Nov
vol. 0,
no. 0,
pp.1-10,
2022.
10
Z. Ayar Dulabi, M. Shafieian, Omid Sabzevari, Zahra Hassannejad, "Modification of the alginate hydrogel with fibroblast- and Schwann cell-derived extracellular matrix potentiates differentiation of mesenchymal stem cells toward neuron-like cells", Journal of Applied Polymer Science, 2022 Sep
vol. 139,
no. 33,
pp.1-14,
2022.
11
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Morphological changes in glial cells arrangement under mechanical loading: A quantitative study", Injury-International Journal of The Care of The Injured, 2022 Aug
vol. 53,
no. 11,
pp.3617-3623,
2022.
12
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Morphological Changes in Glial Cell Arrangement under Mechanical Loading: A Quantitative Study", Injury-International Journal of The Care of The Injured, 2022 Aug
vol. 53,
no. 11,
pp.3617-3623,
2022.
13
Milad Rahimzadegan, Q. Mohammadi, M. Shafieian, Omid Sabzevari, Zahra Hassannejad, "Influence of reducing agents on in situ synthesis of gold nanoparticles and scaffold conductivity with emphasis on neural differentiation", Materials Science and Engineering C-Materials For Biological Applications, 2022 Feb
vol. 1,
no. 1,
pp.1-14,
2022.
14
Mohammadreza Tabari, Sadegh Ahmadi, Mohammad Hoseinamirzade-iranaq, Maryamshojaei, Masoudsohrabi Asl, Zahraghodsi, Amir Azarhomayoun, Alireza Ansari-moghaddam, Rasha Atlasi, Farnaz Araghi, M. Shafieian, Seyed-taghi Heydari, Mahdi Shari-alhoseini, Gerardo'reilly, Vafa Rahimi-movaghar, "The effectiveness of different types of motorcycle helmets-A scoping review", Accident Analysis and Prevention, 2021 May
vol. 154,
no. 1,
pp.1-13,
2021.
15
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "The Importance of Axonal Directions in the Brainstem Injury during Neurosurgical Interventions", Injury-International Journal of The Care of The Injured, 2021 May
vol. 52,
no. 6,
pp.1271-1276,
2021.
16
Z. Ayar Dulabi, M. Shafieian, Narges Mahmoodi, Omid Sabzevari, Zahra Hassannejad, "A rechargeable drug delivery system based on pNIPAM hydrogel for the local release of curcumin", Journal of Applied Polymer Science, 2021 May
vol. 138,
no. 40,
pp.1-13,
2021.
17
F. Eskandari, Z. Rahmani Hamzehkolaei, M. Shafieian, "The effect of large deformation on Poisson's ratio of brain white matter: An experimental study", Proceedings of The Institution of Mechanical Engineers Part H-Journal of Engineering In Medicine, 2020 Dec
vol. 235,
no. 4,
pp.401-407,
2020.
18
Z. Rahmani Hamzehkolaei, M. Shafieian, "The effect of large deformation on Poisson's ratio of brain white matter: An experimental study", Proceedings of The Institution of Mechanical Engineers Part H-Journal of Engineering In Medicine, 2020 Dec
vol. 235,
no. 4,
pp.401-407,
2020.
19
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Mind the gap: A mechanobiological hypothesis for the role of gap junctions in the mechanical properties of injured brain tissue", Journal of The Mechanical Behavior of Biomedical Materials, 2020 Nov
vol. 115,
no. 1,
pp.1-4,
2020.
20
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Mind the gap: A mechanobiological hypothesis for the role of gap junctions in the mechanical properties of injured brain tissue", Journal of The Mechanical Behavior of Biomedical Materials, 2020 Nov
vol. 115,
no. 1,
pp.1-6,
2020.
21
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "The Importance of Axonal Directions in the Brainstem Injury during Neurosurgical Interventions", Injury-International Journal of The Care of The Injured, 2020 Oct
vol. 51,
no. 10,
pp.1-10,
2020.
22
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Structural Anisotropy vs. Mechanical Anisotropy: The Contribution of Axonal Fibers to the Material Properties of Brain White Matter", Annals of Biomedical Engineering, 2020 Oct
vol. 48,
no. 10,
pp.1-9,
2020.
23
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Structural Anisotropy vs. Mechanical Anisotropy: The Contribution of Axonal Fibers to the Material Properties of Brain White Matter", Annals of Biomedical Engineering, 2020 Oct
vol. 49,
no. 1,
pp.991-999,
2020.
24
Z. Eivazi Zadeh, A. Solouk Mofrad, M. Shafieian, M. Haghbin Nazarpak, "Electrospun Polyurethane/Carbon Nanotube Composites with Different Amounts of Carbon Nanotubes and Almost the Same Fiber Diameter for Biomedical Applications", Materials Science and Engineering C-Materials For Biological Applications, 2020 Aug
vol. 2,
no. 1,
pp.1-10,
2020.
25
E. Entekhabi, M. Haghbin Nazarpak, M. Shafieian, H. Mohammadi, Masoumeh Firouzi, Zahra Hassannejad, "Fabrication and in vitro evaluation of 3D composite scaffold based on collagen/hyaluronic acid sponge and electrospun PCL nanofibers for peripheral nerve regeneration.", Journal of Biomedical Materials Research Part A, 2020 Jun
vol. 108,
no. 8,
pp.1-10,
2020.
26
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Tension Strain-Softening and Compression Strain-Stiffening Behavior of Brain White Matter", Annals of Biomedical Engineering, 2020 Jun
vol. 48,
no. 0,
,
2020.
27
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "Tension strain-softening and compression strain-stiffening behavior of brain white matter", Annals of Biomedical Engineering, 2020 Jun
vol. 49,
no. 1,
pp.276-286,
2020.
28
M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "A knowledge map analysis of brain biomechanics: Current evidence and future directions", Clinical Biomechanics, 2020 Apr
vol. 75,
no. 1,
pp.1-11,
2020.
29
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari, "A knowledge map analysis of brain biomechanics: Current evidence and future directions", Clinical Biomechanics, 2020 Mar
vol. 75,
no. 0,
,
2020.
30
F. Askari Siahooei, M. Shafieian, A. Solouk Mofrad, S.A. Hashemi, "A comparison of the material properties of natural and synthetic vascular walls", Journal of The Mechanical Behavior of Biomedical Materials, 2017 Mar
vol. 71,
no. 1,
pp.209-215,
2017.
31
F. Askari Siahooei, A. Solouk Mofrad, M. Shafieian, Alexander Seifalian, "Stem cells for tissue engineered vascular bypass grafts", Artificial Cells Nanomedicine and Biotechnology, 2016 Jun
vol. 0,
no. 0,
pp.1-12,
2016.
32
B. Farhang, F. Rezayaraghi, Aram Bahmani, F. Moztarzadeh, M. Shafieian, "Landing impact analysis of sport surfaces using three-dimensional finite element model", Proceedings of The Institution of Mechanical Engineers Part P-Journal of Sports Engineering and Technology, 2015 May
vol. 230,
no. 3,
pp.180-185,
2015.
33
M. Shafieian, "A microcontinuum model for mechanical properties of esophageal tissue: experimental methodology and constitutive analysis.", Annals of Biomedical Engineering, 2013 Dec
vol. 42,
no. 1,
pp.62-72,
2013.
Conference Papers
1
Z. Azizi, M. Sabzeh Parvar, , M. Shafieian,
"The Effect of Cerebrospinal Fluid on the Mechanical Response of the Brain under Space Launch-Induced Hypergravity,",
The 34th Annual International Conference of Iranian Society of Mechanical Engineers, Jul 2026.
2
P. Pourreza, , A. Fatemeh, M. Shafieian,
"Cell-Substrate Interactions: Finite Element Modeling of Cell Mechanical Responses to Micropillar Substrates,",
31st National and 9th International Iranian Conference on Biomedical Engineering, Nov 2024.
3
M. Zare Gachi, A. Solouk Mofrad, M. Shafieian, Hamed Daemi,
"Fabrication of Cationic Antibiotic Affinity-Based Sulfated Alginate Nanofibers for Drug Delivery,",
22nd Iranian Chemical Congress, May 2024.
4
Ali Allahgholi, A. Mazhari, M. Shafieian,
"Automated Detection of SDH and EDH Due to TBI from CT-Scan Images Using CNN,",
30th National and 8th International Iranian Conference on Biomedical Engineering, Nov 2023.
5
F. Jahani, M. Shafieian, M. Nabaei,
"Estimation of Size and Depth of a Breast Tumor Using Thermal Analysis; A Numerical Study,",
30th National and 8th International Iranian Conference on Biomedical Engineering (ICBME), Nov 2023.
6
A. Allahdinian, , M. Shafieian,
"The Role of Glial Cells in the Mechanical Behavior of Brain Tissue: A Mechanobiological Approach,",
29th National and 7th International Iranian Conference on Biomedical Engineering (ICBME 2022), Dec 2022.
7
A. Allahdinian, , M. Shafieian,
"The Role of Glial Cells in the Mechanical Behavior of Brain Tissue: A Mechanobiological Approach,",
29th National and 7th International Iranian Conference on Biomedical Engineering (ICBME 2022), Dec 2022.
8
A. Allahdinian, F. Eskandari, M. Shafieian,
"The Role of Glial Cells in the Mechanical Behavior of Brain Tissue: A Mechanobiological Approach,",
ICBME, Dec 2022.
9
N. Rahmanifar, F. Eskandari, M. Shafieian,
"Mechanical Characterization of Expanded Polystyrene (EPS) as a Liner Foam in Motorcycle Helmets,",
27th National and 5th International Iranian conference on Biomedical Engineering, Nov 2020.
10
N. Rahmanifar, , M. Shafieian,
"Mechanical Characterization of Expanded Polystyrene (EPS) as a Liner Foam in Motorcycle Helmets,",
27th National and 5th International Iranian conference on Biomedical Engineering, Nov 2020.
11
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari,
"Visco-hyperelastic Properties of White and Gray Matters under Tension: an Ex-vivo Study,",
The 28th Annual International Conference of Iranian Society of Mechanical Engineers-ISME2020, May 2020.
12
F. Eskandari, M. Shafieian, M. Mohammadi Aghdam, Kaveh Laksari,
"Mechanical Properties of Brain White Matter under Repetitive Loading Condition: Introducing a Mechanical Damage Function,",
26th National and 4th International Iranian conference on Biomedical Engineering, Nov 2019.
13
M. Shafieian, Dinesh Mohan,
"Vehicle Safety Post-Decade of Action for Road Safety: The way Forward,",
24th International Conference on Safe Community, Aug 2019.
14
F. Eskandari, M. Mohammadi Aghdam, M. Shafieian,
"The Effect of Compressive Cyclic Loading on the Mechanical and Histological Properties of Brain Tissue,",
American Society of Biomechanics East Coast Meeting, Apr 2019.
15
Z. Eivazi Zadeh, A. Solouk Mofrad, M. Shafieian, M. Haghbin Nazarpak,
"Polyurethane/carbon nanotube (PU/Cnts) nanocomposites as vascular graft substitute: effect of cnts length,",
The First International Iranian Tissue Engineering and Regenerative Medicine Congress :ITERM 2018, Jul 2018.
16
S. Bahramizadeh Sajadi, F. Eskandari, A. Arshi, M. Shafieian,
"a comparative study on spatio-temporal parameters of walking gait of patients with lumbar spinal stenosis and lumbar intervertebral disc degeneration,",
4th international conference on Knowledge-based engineering and innovation, Dec 2017.
17
M. Shafieian, Vafa Rahimi-movaghar,
"What is the Real Number of Road Traffic Crashes in Iran? A Desperate Need for a Road Traffic Crash Registry System,",
2015 IRCOBI Conference Proceedings, Sep 2015.
18
M. Shafieian,
"Crash Analysis: Powerfull Tool to Assess Vehicle Safety,",
The 2nd International Neurotrauma Congress & the 4th International Roads Safety Congress, Feb 2015.
19
F. Askari Siahooei, A. Solouk Mofrad, M. Shafieian,
"Mechanical Characterization of Artificial Blood Vessel Based Polyurethane Nanocomposite and Natural Sheep Artry,",
The First Conferecne on Novel Approaches of Biomedical Engineering in Cardivascular Diseases, Jan 2015.
20
M. Shafieian,
"Field Assessment of Traffic Accidents,",
5th National Traffic Management Conference, May 2014.
21
M. Shafieian,
"Development of a Constitutive Model for Brain Tissue under Multiaxial Loading,",
2012 IRCOBI Conference Proceedings, Sep 2013.
Taught Courses
#
Course title
Description
Headlines
Date
1
Technical Language
4051
2
Viscoelasticity & Rheo. of Bio. Mat.
4051
3
Creativity and Innovation in Biomedical Engineering
این درس با هدف تقویت تفکر خلاق و مهارت حل مسئله نوآورانه در زمینه مهندسی پزشکی طراحی شده است ودر آن موضوعات متنوعی از اصول خلاقیت تا کاربر
4042
4
Technical Language
توانمندسازی دانشجویان مهندسی پزشکی برای درک متون علمی و فنی، برقراری ارتباط مؤثر در محیط های بین المللی و به روزرسانی دانش تخصصی خود از ط
4042
5
Statics and Strength of Materials
آشنایی دانشجویان با مفاهیم بنیادی تعادل اجسام صلب و تحلیل رفتار مکانیکی اعضای سازه ای تحت اثر نیروهای وارده، به منظور ایجاد توانایی تحلی
4042
6
Impact Biomechanics
4032
7
Statics and Strength of Materials
4032
8
Technical Language
4022
9
Impact Biomechanics
4022
10
Statics and Strength of Materials
4022